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Innovations in medicine

   

The Balloon Embolectomy Catheter

 is a wonderful example of simple inventions resulting in a powerful medical breakthrough. This invention pioneered minimally invasive vascular surgery, and extended life saving procedures to ten's of millions of people.

  Surgeon Thomas J. Fogarty, M.D. as professor, inventor and entrepreneur, has saved tens of millions of lives by pioneering the tools and methods of less invasive vascular surgery. Before earning his MD in 1960 from the University of Cincinnati Medical School, Fogarty had conceived and designed his most significant invention. The Fogarty Balloon Embolectomy Catheter is, like many revolutionary medical innovations, simple in concept.

It is comprised of a hollow tube about the width of a pencil, with a small inflatable balloon attached at tip. The catheter is inserted through an incision into a blood vessel, and pressed through a blood clot; the balloon is inflated, so it can displace the clot as it is extracted from the vessel.

Fogarty built the first prototype in his attic using his boyhood fly-tying kit familiar to him from his regular fishing trips. Employing his dexterity he attached the fingertip of a latex surgical glove to the hollow tube. Fogarty's balloon catheter procedure was the first successful example of "less-invasive" vascular surgery.

Meridia


 The most important information about Meridia

Meridia has been reported to cause increased blood pressure in some patients. It is important to have your blood pressure and pulse monitored regularly while taking Meridia.

Use caution when driving, operating machinery, or performing other hazardous activities. Meridia may cause dizziness, difficulty concentrating, or restlessness. If you experience these effects, avoid hazardous activities.

Do not take any other prescription or over-the-counter medicines without first talking to your doctor, especially weight-loss products, tryptophan (L-tryptophan, 5-HTP), decongestants, antidepressants, cough suppressants, lithium (Eskalith, Lithobid, Lithonate, others), and migraine medicines.

 

What is Meridia

Meridia affects chemicals in the body that are related to weight maintenance.

Meridia is used as a short-term supplement to diet and exercise in the treatment of obesity.

Meridia may also be used for purposes other than those listed in this medication guide.

What should I discuss with my healthcare provider before taking Meridia?

Do not take Meridia without first talking to your doctor if you have taken a monoamine oxidase inhibitor (MAOI) such as isocarboxazid (Marplan), tranylcypromine (Parnate), or phenelzine (Nardil) in the last 14 days;

have anorexia nervosa;

are taking an appetite suppressant;

have high blood pressure;

have heart disease, irregular heartbeats, congestive heart failure, or a history of stroke;

have epilepsy or another seizure disorder;

have gallstones;

have glaucoma;

have liver disease; or

have kidney disease.

You may not be able to take Meridia, or you may require a dosage adjustment or special monitoring if you have any of the conditions listed above.

Meridia is in the FDA pregnancy category C. This means that it is not known whether Meridia will harm an unborn baby. Do not take Meridia without first talking to your doctor if you are pregnant or could become pregnant during treatment.

It is not known whether Meridia passes into breast milk. Do not take Meridia without first talking to your doctor if you are breast-feeding a baby.

The safety and effectiveness of Meridia have not been studied in children younger than 16 years of age.

How should I take Meridia?

Take Meridia exactly as directed by your doctor. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you.

Take each dose with a full glass of water.

Meridia is usually taken once a day. Follow your doctor's instructions.

Meridia can be taken with or without food.

Never take more of this medication than is prescribed for you. Too much Meridia could be dangerous.

Meridia has been reported to cause increased blood pressure in some patients. It is important to have your blood pressure and pulse monitored regularly while taking Meridia.

Store Meridia at room temperature away from moisture and heat.

 

In case of missing a dose

 Take the missed dose as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and take only the next regularly scheduled dose. Do not take a double dose of this medication.

 

In case of I overdosing

Seek emergency medical attention.                                                               

Symptoms of a Meridia overdose are not known.

What to avoid while taking Meridia

Use caution when driving, operating machinery, or performing other hazardous activities. Meridia may cause dizziness, difficulty concentrating, or restlessness. If you experience these effects, avoid hazardous activities.

Do not take any other prescription or over-the-counter medicines without first talking to your doctor, especially weight-loss products, tryptophan (L-tryptophan, 5-HTP), decongestants, antidepressants, cough suppressants, lithium (Eskalith, Lithobid, Lithonate, others), and migraine medicines.

The possible side effects of Meridia

If you experience any of the following serious side effects, stop taking Meridia and seek emergency medical attention or contact your doctor immediately:

an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives);

an irregular heartbeat;

high blood pressure (severe headache, blurred vision); or

seizures.

Other, less serious side effects may be more likely to occur. Continue to take Meridia and talk to your doctor if you experience

restlessness or tremor,

nervousness or anxiety,

mild headache or dizziness,

insomnia,

dry mouth or an unpleasant taste in your mouth, or

constipation.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

 

What other drugs will affect Meridia

Do not take Meridia if you have taken a monoamine oxidase inhibitor (MAOI) such as isocarboxazid (Marplan), tranylcypromine (Parnate), or phenelzine (Nardil) in the last 14 days. A dangerous drug interaction may occur.

Before taking this medication your doctor should know that you take

lithium (Lithobid, Eskalith, Lithonate, others);

almotriptan (Axert), naratriptan (Amerge), rizatriptan (Maxalt), sumatriptan (Imitrex), or zolmitriptan (Zomig);

citalopram (Celexa), fluoxetine (Prozac), sertraline (Zoloft), paroxetine (Paxil), or fluvoxamine (Luvox);

venlafaxine (Effexor), nefazodone (Serzone), mirtazapine (Remeron), or thioridazine (Mellaril);

amitriptyline (Elavil, Endep), amoxapine (Asendin), clomipramine (Anafranil), desipramine (Norpramin), doxepin (Sinequan), imipramine (Tofranil), nortriptyline (Pamelor), protriptyline (Vivactil), or trimipramine (Surmontil);

dihydroergotamine (D.H.E.);

dextromethorphan (in many cough medicines);

meperidine (Demerol);

fentanyl (Duragesic); or

pentazocine (Talacen, Talwin).

Meridia may interact with the medicines listed above and cause anxiety, restlessness, loss of consciousness, confusion, weakness, tremor, poor coordination, fever, shivering, sweating, vomiting, a fast heartbeat, and other symptoms. These reactions can be very dangerous and require medical attention. Do not take any other prescription or over-the-counter medicines without first talking to your doctor, especially weight-loss products, tryptophan (L-tryptophan, 5-HTP), decongestants, antidepressants, cough suppressants, lithium (Eskalith, Lithobid, Lithonate, others), or migraine medicines.

Drugs other than those listed here may also interact with Meridia. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines.

 

 

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