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Innovations in medicine

   

The Balloon Embolectomy Catheter

 is a wonderful example of simple inventions resulting in a powerful medical breakthrough. This invention pioneered minimally invasive vascular surgery, and extended life saving procedures to ten's of millions of people.

  Surgeon Thomas J. Fogarty, M.D. as professor, inventor and entrepreneur, has saved tens of millions of lives by pioneering the tools and methods of less invasive vascular surgery. Before earning his MD in 1960 from the University of Cincinnati Medical School, Fogarty had conceived and designed his most significant invention. The Fogarty Balloon Embolectomy Catheter is, like many revolutionary medical innovations, simple in concept.

It is comprised of a hollow tube about the width of a pencil, with a small inflatable balloon attached at tip. The catheter is inserted through an incision into a blood vessel, and pressed through a blood clot; the balloon is inflated, so it can displace the clot as it is extracted from the vessel.

Fogarty built the first prototype in his attic using his boyhood fly-tying kit familiar to him from his regular fishing trips. Employing his dexterity he attached the fingertip of a latex surgical glove to the hollow tube. Fogarty's balloon catheter procedure was the first successful example of "less-invasive" vascular surgery.

Lamisil


The most important information about Lamisil

• Take all of the Lamisil that has been prescribed for you even if you begin to feel better. The symptoms may begin to improve before the infection is completely treated.
• In rare cases, Lamisil has caused severe liver damage, sometimes resulting in liver transplant or death. Notify your doctor immediately if you develop nausea, vomiting, abdominal pain, unusual fatigue, loss of appetite, yellow skin or eyes, itching, dark urine, or clay colored stools. These symptoms may be early signs of liver damage.


What is Lamisil

• Lamisil is an antifungal medication. It is like an antibiotic but is used to treat fungal infections.
• Lamisil is used to treat fungal infections of the fingernails and toenails.
• Lamisil may also be used for purposes other than those listed in this medication guide.


What to discuss with your doctor before taking Lamisil

• Do not take Lamisil without first talking to your doctor if you have
· ever had an allergic reaction to it,
· liver disease,
· kidney disease,
· problems with your immune system, or
· blood problems.
• You may not be able to take Lamisil, or you may require a dosage adjustment or special monitoring if you have any of the conditions listed above.
• Lamisil is in the FDA pregnancy category B. This means that it is not expected to harm an unborn baby. Do not take Lamisil without first talking to your doctor if you are pregnant.
• Lamisil passes into breast milk and may affect a nursing baby. Do not take this medication without first talking to your doctor if you are breast-feeding a baby.


How to take Lamisil

• Take Lamisil exactly as directed by your doctor. If you do not understand these instructions, ask your pharmacist, nurse, or doctor to explain them to you.
• Take each dose with a full glass (8 ounces) of water.
• Take all of the Lamisil that has been prescribed for you even if you begin to feel better. The symptoms may begin to improve before the infection is completely treated. It may take several months to cure a fingernail or toenail infection.
• Store this medication at room temperature away from moisture and heat.


What happens in case of missing a dose

• Take the missed dose as soon as you remember. However, if it is almost time for the next regularly scheduled dose, skip the missed dose and take the next one as directed. Do not take a double dose of this medication.


What happens i.n case of overdosing

• Seek emergency medical attention.
• Symptoms of a Lamisil overdose are not well known but might include drowsiness, poor coordination, shortness of breath, abdominal pain, frequent urination, rash, and headache.


What to avoid while taking Lamisil

• Avoid alcohol or use it in moderation while taking Lamisil. Alcohol and Lamisil can both affect the liver.


The possible side effects of Lamisil

• If you experience any of the following serious side effects, stop taking Lamisil and seek emergency medical attention:
· an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives);
· a rash;
· changes in vision; or
· blood problems (detected by blood tests).
• In rare cases, Lamisil has caused severe liver damage, sometimes resulting in liver transplant or death. Notify your doctor immediately if you develop nausea, vomiting, abdominal pain, unusual fatigue, loss of appetite, yellow skin or eyes, itching, dark urine, or clay colored stools. These symptoms may be early signs of liver damage.
• Other, less serious side effects may be more likely to occur. Continue to take Lamisil and talk to your doctor if you experience
· nausea, upset stomach, or heartburn;
· diarrhea or flatulence;
· headache; or
· taste disturbances or a loss of taste.
• Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.


Other drugs affect Lamisil

• Before taking Lamisil, tell your doctor if you are taking any of the following medicines:
· cimetidine (Tagamet, Tagamet HB).;
· rifampin (Rifadin, Rimactane); or
· cyclosporine (Sandimmune, Neoral).
• You may not be able to take Lamisil, or you may require a dosage adjustment or special monitoring during treatment if you are taking any of the medicines listed above.
• Drugs other than those listed here may also interact with Lamisil. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines.


Where to get more information

• Your pharmacist has additional information about Lamisil written for health professionals that you may read.
• Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
• Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
Click here for more information on Lamisil from the manufacturer.
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