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Innovations in medicine

   

The Balloon Embolectomy Catheter

 is a wonderful example of simple inventions resulting in a powerful medical breakthrough. This invention pioneered minimally invasive vascular surgery, and extended life saving procedures to ten's of millions of people.

  Surgeon Thomas J. Fogarty, M.D. as professor, inventor and entrepreneur, has saved tens of millions of lives by pioneering the tools and methods of less invasive vascular surgery. Before earning his MD in 1960 from the University of Cincinnati Medical School, Fogarty had conceived and designed his most significant invention. The Fogarty Balloon Embolectomy Catheter is, like many revolutionary medical innovations, simple in concept.

It is comprised of a hollow tube about the width of a pencil, with a small inflatable balloon attached at tip. The catheter is inserted through an incision into a blood vessel, and pressed through a blood clot; the balloon is inflated, so it can displace the clot as it is extracted from the vessel.

Fogarty built the first prototype in his attic using his boyhood fly-tying kit familiar to him from his regular fishing trips. Employing his dexterity he attached the fingertip of a latex surgical glove to the hollow tube. Fogarty's balloon catheter procedure was the first successful example of "less-invasive" vascular surgery.

Zithromax


 

The most important information  about Zithromax

• Do not use Zithromax if you have ever had an allergic reaction to this medicine or similar drugs such as erythromycin (E-Mycin, Ery-Tab, E.E.S.), clarithromycin (Biaxin), or other macrolide antibiotics.
• There are many other medicines that can interact with Zithromax. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor. Keep a list with you of all the medicines you use and show this list to any doctor or other healthcare provider who treats you.
• Take this medication for the entire length of time prescribed by your doctor. Your symptoms may get better before the infection is completely treated. Zithromax will not treat a viral infection such as the common cold or flu.
• Take Zithromax on an empty stomach 1 hour before or 2 hours after meals.
• Do not take Zithromax at the same time as taking an antacid that contains aluminum or magnesium. This includes Rolaids, Maalox, Mylanta, Milk of Magnesia, Pepcid Complete, and others. These antacids can make Zithromax less effective when taken at the same time.


What is Zithromax?

• Zithromax is in a group of drugs called macrolide antibiotics. Zithromax fights bacteria in the body.
• Zithromax is used to treat many different types of infections caused by bacteria, such as respiratory infections, skin infections, ear infections, and sexually transmitted diseases.
• Zithromax may also be used for purposes other than those listed in this medication guide.


What to discuss with your doctor before taking Zithromax

• Do not use Zithromax if you have ever had an allergic reaction to this medicine or similar drugs such as erythromycin (E-Mycin, Ery-Tab, E.E.S.), clarithromycin (Biaxin), or other macrolide antibiotics.
• Before taking Zithromax, tell your doctor if you have:
· liver disease;
· kidney disease;
· a heart rhythm disorder; or
· a history of Long QT syndrome.
• If you have any of these conditions, you may not be able to use Zithromax, or you may need a dosage adjustment or special tests during treatment.
• FDA pregnancy category B. This medication is not expected to be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment.
• It is not known whether Zithromax passes into breast milk or if it could harm a nursing baby. Do not take this medication without telling your doctor if you are breast-feeding a baby.


How to take Zithromax

• Take this medication exactly as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor. The dose and length of treatment with Zithromax may not be the same for every type of infection.
• Take each tablet or capsule with a full glass (8 ounces) of water.
• To use the oral suspension single dose packet: Open the packet and pour the medicine into 2 ounces of water. Stir this mixture and drink all of it right away. To make sure you get the entire dose, add a little more water to the same glass, swirl gently and drink right away.
• Zithromax capsules must be taken on an empty stomach. Take the capsule at least 1 hour before or 2 hours after eating a meal
• Zithromax tablets or powder oral suspension may be taken with or without food. Take the tablet or oral suspension with food if the medicine upsets your stomach.
• Do not take Zithromax at the same time as taking an antacid that contains aluminum or magnesium. This includes Rolaids, Maalox, Mylanta, Milk of Magnesia, Pepcid Complete, and others. These antacids can make Zithromax less effective when taken at the same time.
• Shake the oral suspension (liquid) well just before you measure a dose. To be sure you get the correct dose, measure the liquid with a marked measuring spoon or medicine cup, not with a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one.
• Take this medication for the entire length of time prescribed by your doctor. Your symptoms may get better before the infection is completely treated. Zithromax will not treat a viral infection such as the common cold or flu.
• It is important to take Zithromax regularly to get the most benefit.
• Store this medication at room temperature away from moisture and heat. Throw away any unused liquid medicine after 10 days.


What happens in case of  missing a dose

• Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at the next regularly scheduled time. Do not take extra medicine to make up the missed dose.


What happens in case of  overdosing

• Seek emergency medical attention if you think you have used too much of this medicine.
• Symptoms of an Zithromax overdose may include nausea, vomiting, diarrhea, and stomach discomfort.


What to avoid while taking Zithromax

• Antibiotic medicines can cause diarrhea, which may be a sign of a new infection. If you have diarrhea that is watery or has blood in it, call your doctor. Do not use any medicine to stop the diarrhea unless your doctor has told you to.
• Avoid exposure to sunlight or artificial UV rays (sunlamps or tanning beds). Zithromax can make your skin more sensitive to sunlight and sunburn may result. Use a sunscreen (minimum SPF 15) and wear protective clothing if you must be out in the sun.

The possible side effects of Zithromax

• Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
• Stop using Zithromax and call your doctor at once if you have any of these serious side effects:
· diarrhea that is watery or bloody;
· chest pain, uneven heartbeats; or
· nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).
• Continue using Zithromax and talk with your doctor if you have any of these less serious side effects:
· mild nausea, vomiting, diarrhea, constipation, or stomach pain;
· dizziness, tired feeling, or headache;
· vaginal itching or discharge; or
· mild itching or skin rash.
• Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.


Other drugs which affect Zithromax

• Do not take antacids that contain aluminum or magnesium within 2 hours of taking Zithromax.
• Before taking Zithromax, tell your doctor if you are using any of the following drugs:
· nelfinavir (Viracept);
· digoxin (Lanoxin, Lanoxicaps);
· ergot medicine such as methysergide (Sansert), ergotamine (Ergostat, Medihaler, Cafergot, Ercaf, Wigraine), dihydroergotamine mesylate (D.H.E., Migranal Nasal Spray);
· triazolam (Halcion);
· carbamazepine (Carbatrol, Tegretol);
· cyclosporine (Neoral, Sandimmune);
· phenytoin (Dilantin);
· cholesterol-lowering medicines such as lovastatin (Mevacor), atorvastatin (Lipitor), or cerivastatin (Baycol);
· a calcium channel blocker such as diltiazem (Cartia XT, Diltiazem, Tiazac), felodipine (Plendil), nicardipine (Cardene), nifedipine (Procardia, Adalat), nimodipine (Nimotop), verapamil (Calan, Covera-HS);
· HIV medicines such as indinavir (Crixivan), ritonavir (Norvir), saquinavir (Invirase);
· alprazolam (Xanax), diazepam (Valium), midazolam (Versed), triazolam (Halcion);
· theophylline (Theo-Dur, Theolair, Theochron);
· warfarin (Coumadin);
· pimozide (Orap); or
· another antibiotic, especially clarithromycin (Biaxin) or erythromycin (E-Mycin, E.E.S, Ery-Tab).
• If you are using any of these drugs, you may not be able to use Zithromax, or you may need dosage adjustments or special tests during treatment.
• There are many other medicines that can interact with Zithromax. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor. Keep a list with you of all the medicines you use and show this list to any doctor or other healthcare provider who treats you.

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